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Chapter 3: Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)

Code Range: D50 — D89 7 Sections FY 2026

This chapter of the ICD-10-CM classification covers diagnosis codes from D50 through D89. Browse the sections below to find specific diagnosis codes within this chapter.

Chapter Notes

Excludes2 (not included here):

  • autoimmune disease (systemic) NOS (M35.9)
  • certain conditions originating in the perinatal period (P00-P96)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • human immunodeficiency virus [HIV] disease (B20)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

Sections

  • D50-D53 Nutritional anemias (D50-D53)
    23 codes
  • D55-D59 Hemolytic anemias (D55-D59)
    96 codes
  • D60-D64 Aplastic and other anemias and other bone marrow failure syndromes (D60-D64)
    37 codes
  • D65-D69 Coagulation defects, purpura and other hemorrhagic conditions (D65-D69)
    50 codes
  • D70-D77 Other disorders of blood and blood-forming organs (D70-D77)
    77 codes
  • D78 Intraoperative and postprocedural complications of the spleen (D78)
    18 codes
  • D80-D89 Certain disorders involving the immune mechanism (D80-D89)
    100 codes

Top-Level Codes in This Chapter

  • D50 Iron deficiency anemia
  • D51 Vitamin B12 deficiency anemia
  • D52 Folate deficiency anemia
  • D53 Other nutritional anemias
  • D55 Anemia due to enzyme disorders
  • D56 Thalassemia
  • D57 Sickle-cell disorders
  • D58 Other hereditary hemolytic anemias
  • D59 Acquired hemolytic anemia
  • D60 Acquired pure red cell aplasia [erythroblastopenia]
  • D61 Other aplastic anemias and other bone marrow failure syndromes
  • D62 Acute posthemorrhagic anemia Billable
  • D63 Anemia in chronic diseases classified elsewhere
  • D64 Other anemias
  • D65 Disseminated intravascular coagulation [defibrination syndrome] Billable
  • D66 Hereditary factor VIII deficiency Billable
  • D67 Hereditary factor IX deficiency Billable
  • D68 Other coagulation defects
  • D69 Purpura and other hemorrhagic conditions
  • D70 Neutropenia
  • D71 Functional disorders of polymorphonuclear neutrophils
  • D72 Other disorders of white blood cells
  • D73 Diseases of spleen
  • D74 Methemoglobinemia
  • D75 Other and unspecified diseases of blood and blood-forming organs
  • D76 Other specified diseases with participation of lymphoreticular and reticulohistiocytic tissue
  • D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere Billable
  • D78 Intraoperative and postprocedural complications of the spleen
  • D80 Immunodeficiency with predominantly antibody defects
  • D81 Combined immunodeficiencies
  • D82 Immunodeficiency associated with other major defects
  • D83 Common variable immunodeficiency
  • D84 Other immunodeficiencies
  • D86 Sarcoidosis
  • D89 Other disorders involving the immune mechanism, not elsewhere classified

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