Chapter 18: Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R99)

Code Range: R00 — R99 14 Sections FY 2026

This chapter of the ICD-10-CM classification covers diagnosis codes from R00 through R99. Browse the sections below to find specific diagnosis codes within this chapter.

Chapter Notes

This chapter includes symptoms, signs, abnormal results of clinical or other investigative procedures, and ill-defined conditions regarding which no diagnosis classifiable elsewhere is recorded.
Signs and symptoms that point rather definitely to a given diagnosis have been assigned to a category in other chapters of the classification. In general, categories in this chapter include the less well-defined conditions and symptoms that, without the necessary study of the case to establish a final diagnosis, point perhaps equally to two or more diseases or to two or more systems of the body. Practically all categories in the chapter could be designated 'not otherwise specified', 'unknown etiology' or 'transient'. The Alphabetical Index should be consulted to determine which symptoms and signs are to be allocated here and which to other chapters. The residual subcategories, numbered .8, are generally provided for other relevant symptoms that cannot be allocated elsewhere in the classification.
The conditions and signs or symptoms included in categories R00-R94 consist of:
(a) cases for which no more specific diagnosis can be made even after all the facts bearing on the case have been investigated;
(b) signs or symptoms existing at the time of initial encounter that proved to be transient and whose causes could not be determined;
(c) provisional diagnosis in a patient who failed to return for further investigation or care;
(d) cases referred elsewhere for investigation or treatment before the diagnosis was made;
(e) cases in which a more precise diagnosis was not available for any other reason;
(f) certain symptoms, for which supplementary information is provided, that represent important problems in medical care in their own right.

Excludes2 (not included here):

abnormal findings on antenatal screening of mother (O28.-)
certain conditions originating in the perinatal period (P04-P96)
signs and symptoms classified in the body system chapters
signs and symptoms of breast (N63, N64.5)

Sections

R00-R09 Symptoms and signs involving the circulatory and respiratory systems (R00-R09)
73 codes
R10-R19 Symptoms and signs involving the digestive system and abdomen (R10-R19)
120 codes
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue (R20-R23)
31 codes
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems (R25-R29)
87 codes
R30-R39 Symptoms and signs involving the genitourinary system (R30-R39)
54 codes
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behavior (R40-R46)
97 codes
R47-R49 Symptoms and signs involving speech and voice (R47-R49)
25 codes
R50-R69 General symptoms and signs (R50-R69)
88 codes
R70-R79 Abnormal findings on examination of blood, without diagnosis (R70-R79)
59 codes
R80-R82 Abnormal findings on examination of urine, without diagnosis (R80-R82)
31 codes
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis (R83-R89)
109 codes
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis (R90-R94)
85 codes
R97 Abnormal tumor markers (R97)
7 codes
R99 Ill-defined and unknown cause of mortality (R99)
1 code

Top-Level Codes in This Chapter

R00 Abnormalities of heart beat
R01 Cardiac murmurs and other cardiac sounds
R03 Abnormal blood-pressure reading, without diagnosis
R04 Hemorrhage from respiratory passages
R05 Cough
R06 Abnormalities of breathing
R07 Pain in throat and chest
R09 Other symptoms and signs involving the circulatory and respiratory system
R10 Abdominal and pelvic pain
R11 Nausea and vomiting
R12 Heartburn Billable
R13 Aphagia and dysphagia
R14 Flatulence and related conditions
R15 Fecal incontinence
R16 Hepatomegaly and splenomegaly, not elsewhere classified
R17 Unspecified jaundice Billable
R18 Ascites
R19 Other symptoms and signs involving the digestive system and abdomen
R20 Disturbances of skin sensation
R21 Rash and other nonspecific skin eruption Billable
R22 Localized swelling, mass and lump of skin and subcutaneous tissue
R23 Other skin changes
R25 Abnormal involuntary movements
R26 Abnormalities of gait and mobility
R27 Other lack of coordination
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
R30 Pain associated with micturition
R31 Hematuria
R32 Unspecified urinary incontinence Billable
R33 Retention of urine
R34 Anuria and oliguria Billable
R35 Polyuria
R36 Urethral discharge
R37 Sexual dysfunction, unspecified Billable
R39 Other and unspecified symptoms and signs involving the genitourinary system
R40 Somnolence, stupor and coma
R41 Other symptoms and signs involving cognitive functions and awareness
R42 Dizziness and giddiness Billable
R43 Disturbances of smell and taste
R44 Other symptoms and signs involving general sensations and perceptions
R45 Symptoms and signs involving emotional state
R46 Symptoms and signs involving appearance and behavior
R47 Speech disturbances, not elsewhere classified
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified
R49 Voice and resonance disorders
R50 Fever of other and unknown origin
R51 Headache
R52 Pain, unspecified Billable
R53 Malaise and fatigue
R54 Age-related physical debility Billable
R55 Syncope and collapse Billable
R56 Convulsions, not elsewhere classified
R57 Shock, not elsewhere classified
R58 Hemorrhage, not elsewhere classified Billable
R59 Enlarged lymph nodes
R60 Edema, not elsewhere classified
R61 Generalized hyperhidrosis Billable
R62 Lack of expected normal physiological development in childhood and adults
R63 Symptoms and signs concerning food and fluid intake
R64 Cachexia Billable
R65 Symptoms and signs specifically associated with systemic inflammation and infection
R68 Other general symptoms and signs
R69 Illness, unspecified Billable
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
R71 Abnormality of red blood cells
R73 Elevated blood glucose level
R74 Abnormal serum enzyme levels
R75 Inconclusive laboratory evidence of human immunodeficiency virus [HIV] Billable
R76 Other abnormal immunological findings in serum
R77 Other abnormalities of plasma proteins
R78 Findings of drugs and other substances, not normally found in blood
R79 Other abnormal findings of blood chemistry
R80 Proteinuria
R81 Glycosuria Billable
R82 Other and unspecified abnormal findings in urine
R83 Abnormal findings in cerebrospinal fluid
R84 Abnormal findings in specimens from respiratory organs and thorax
R85 Abnormal findings in specimens from digestive organs and abdominal cavity
R86 Abnormal findings in specimens from male genital organs
R87 Abnormal findings in specimens from female genital organs
R88 Abnormal findings in other body fluids and substances
R89 Abnormal findings in specimens from other organs, systems and tissues
R90 Abnormal findings on diagnostic imaging of central nervous system
R91 Abnormal findings on diagnostic imaging of lung
R92 Abnormal and inconclusive findings on diagnostic imaging of breast
R93 Abnormal findings on diagnostic imaging of other body structures
R94 Abnormal results of function studies
R97 Abnormal tumor markers
R99 Ill-defined and unknown cause of mortality Billable

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